Scientist, Next Generation Antibody Discovery- Gaithersburg, MD
Do you have expertise in, and a passion for protein and antibody engineering? Would you like to apply your expertise in Oncology, Respiratory, Inflammatory, Cardiovascular, and Infection Disease in a company that follows the science and turns ideas into life changing medicines? AstraZeneca might be the one for you!
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies.
At AZ, we're proud to have an exceptional workplace culture that encourages innovation and collaboration. Here, employees are empowered to express diverse perspectives - and made to feel valued, energized and rewarded for their ideas and creativity. AZ is a place where passionate people can immerse themselves in their work and make significant contributions to scientific excellence and medicines - does this describe a place where you would like to work?
At AstraZeneca Oncology R&D, we are not afraid to do things differently. Our vision is redefining cancer, redefining our solutions to cancer and restoring patients' lives. In this role, you will join a dynamic and collaborative in vivo biology team in our state-of-the-art Biohub facility in Waltham, MA. The primary responsibilities of this position are to build and characterize hematologic in vivo animal cancer models, conduct PKPD and efficacy studies to support our heme R&D portfolio.
What you'll do:
The Department of Biological Engineering in Gaithersburg, MD is seeking a creative and highly motivated Scientist to implement our next-generation rapid B cell discovery platforms to progress pre-clinical programs. The successful candidate will add to our team of multidisciplinary and passionate scientists excited by research at the interface between technology and Biology. They will be a well-organized and a highly productive bench scientist that can design and execute experiments efficiently, as well as analyze, interpret and present data.
Education, Qualifications, Skills and Experience:Required:
- Perform high-throughput cloning of lead antibody panels using automation
- Design and implement high-throughput automated screening assays for specificity using ELISA, next-generation sequencing and/or FACS
- Use microfluidics to build novel antibody fragment libraries for various display-based systems (such as phage, yeast, and mammalian-display)
- Master's degree in Molecular Biology or related fields with 2+ years of relevant experience in industry (preferred) or academia, or Bachelor's degree in Molecular Biology or related field with 5+ years of relevant experience in industry (preferred) or academia.
- Proven expertise in producing recombinant antibodies, particularly in molecular biology techniques involving cloning, sequencing, PCR and qPCR
- Hands-on experience in sequence analysis, including NGS-based antibody analysis
- Ability to execute experiments, develop assays, optimize protocols, and interpret experimental results
- Strong communication skills in a team environment and an ability to learn and embrace new technologies quickly
- Ability to work in a fast-paced environment with deadline-driven workflows
- Comfortable with using automation for high-throughput sample handling
- Experience with flow-cytometry, protein purification and FACS
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.Site Description
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria, and nature walks. This is where you'll find newly designed, activity-based workspaces to suit a variety of working styles while increasing collaboration between teams.So, what's next?
A place built on courage, curiosity, and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take calculated risks that write the next chapter for our pipeline.
If you are swift to action, confident to lead, willing to collaborate, and passionate about the possibilities, then we are keen to hear from you!Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=enNext steps:
Apply today, or connect with our Talent Acquisition Partner - Kayla Harris: https://www.linkedin.com/in/kayla-harris-8723ab13b/ for a confidential discussion to explore this opportunity further. We are looking forward to hearing from you!
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
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