Senior Scientist - In vitro Immunology for Cell Therapy
AstraZeneca

Job Info

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Are you an experienced scientist in the field of immune cell therapy or immunology? Do you have a passion for regenerative medicine and are you excited by the opportunity to apply your scientific drive to the development of cell-based therapies? Join us and be a key player in the build of our new Biopharmaceuticals R&D Cell Therapy department. Together we will push the boundaries of Science!

At AstraZeneca, you will be empowered to be innovative and creative where difference is valued. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. The role is placed at AstraZeneca's dynamic U.S. R&D site in Gaithersburg, Maryland, where you will work in an international setting at the fore front of Cell Therapy science.

Biopharmaceuticals R&D is committed to the development of next generation innovative medicines, and we are building a Cell Therapy Department with the goal to establish AstraZeneca as a world-leader in Cell Therapy across disease areas within Cardiovascular, Renal and Metabolism (CVRM) and Respiratory and Inflammation (R&I). The Cell Therapy Department will bring together more than 50 specialists across Europe and the U.S. to support the organization with cell therapy expertise and capabilities, whilst working in close collaboration with experts across AstraZeneca globally to leverage the existing and emerging platforms in cell technologies, new modalities, hypoimmunogenic cell lines and genome editing.

What you'll do

Building on your background in immunology you will apply your skills in a regenerative medicine setting, working collaboratively with project leaders, in vitro and in vivo scientists and therapy area specialists to ensure efficient progress of Cell Therapy projects and to drive our scientific capabilities. The role is focused on laboratory-based activities and you will use your scientific expertise to design and execute experiments and to deliver high quality data.

You will play a leading role in developing our scientific capabilities and presenting your work both internally and externally, working in a highly cross disciplinary environment with local and international colleagues.

In this role it is essential to have good social and communication skills, be collaborative and a strong team player. You should be able to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude. Accountabilities include:

• Design and execute experiments to generate high quality, relevant data
  

• Independently assess and report data to support project decisions and milestones
  
• Communicate and share relevant information between distinct projects within the bioscience department as well as across other functions and externally
  
• Keep up to date with relevant scientific literature and technology platforms as well as writing and publishing scientific papers
  

Essential for the role

• Ph.D. in Cell Biology or a related discipline, or a MSc degree with relevant academic or industrial experience.
  
• Strong background in immunology, hands-on experience with developing CAR-T, NK, Treg or other immune cell therapy development preferred
  
• Proficiency in assays interrogating immune cell function, such as cellular activation, cytokine release, proliferation, cytotoxicity, multi-parameter flow cytometry, ELISA/MSD.
  
• Experience with immune cell expansion protocols strongly preferred.
  
• Preferred to have experience editing primary immune cells (e.g. CRISPR technology, Lenti-viral transduction).
  

• Good scientific presentation skills and ability to comfortably present and discuss scientific data.
  
• Good communication skills, a collaborative mindset and a strong team player.
  
• Ability to work independently, take own initiatives and have a positive, goal-oriented and problem-solving attitude.
  

So, what's next?

Are you already imagining yourself joining our team? Excellent! We have several positions available and look forward to your application.

Welcome with your application no later than 23rd January 2023

Where can I find out more?

Cell Therapy Biopharmaceuticals R&D: https://www.astrazeneca.com/r-d/next-generation-therapeutics/cell-therapies.html

Our Gaithersburg site: https://www.astrazeneca.com/our-company/our-locations/gaithersburg.html

Life at AstraZeneca: https://careers.astrazeneca.com/inclusion-diversity

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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