Senior Scientist, T cell Immunology, Oncology Research
AstraZeneca

Gaithersburg, Maryland

Posted in Pharmaceuticals


Job Info


Senior Scientist, T cell Immunology, Oncology Research

Gaithersburg, MD

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We're passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life.

AstraZeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and haematological cancers.

This Opportunity

We are seeking highly motivated Senior Scientists in Immuno-Oncology with scientific and technical expertise in T cell biology with a track record of scientific achievement to join our team in Gaithersburg, US. As a Senior Scientist you will be a key member of a team focused on supporting immune-oncology projects through the drug discovery process. You will bring your theoretical and practical expertise in immunology to establish assay systems and deliver datasets that will have direct impact on immune-oncology research projects.

Main Duties and Responsibilities

AstraZeneca seeks an innovative and highly motivated Senior Scientist with a background in immunology or a related field to join the Early Discovery Oncology Bioscience team in Gaithersburg, MD. As a Senior Scientist you will be a key member of a team focused on supporting Immuno-Oncology projects through the drug discovery process. You will bring your expertise in Immunology to establish assay systems and deliver datasets that will have direct impact on pipeline programs.

Working in this laboratory-based position within the Immuno-Oncology Research group you will develop, conduct and analyze experiments to assess the function of our candidate drugs. You will design novel therapeutics targeting the immune system for cancer therapy and help to dissect their mechanism of action. You will be expected to support cross-functional teams and work collaboratively with colleagues to ensure the timely generation and dissemination of critical program data. You will also review emerging literature and internal data to help in identifying new potential targets and contribute to target validation activities.

A solid foundation in immunology and T cell biology with experience in different in vitro and in vivo assays (including mouse models) for the evaluation of immune cell function is essential for this role. As a highly organized, self-motivated individual with a strong lab/practical background you will stay up to date with relevant techniques and have a genuine passion for this field of research. The position requires strong interest in experimental work and ability to work in a fast-paced matrix structured work environment.

Essential Requirements

  • A PhD, or equivalent experience, in immunology and/or immuno-oncology, with 0-6 years of post-doctoral experience in a relevant research area. Industry experience is a plus but not required.
  • Strong background in immunology and experience with performing standard in vitro assays (immune cell activation, cytotoxic assays, etc) and use of in vivo mouse models.
  • Extensive experience with multi-color flow cytometry to evaluate mouse and/or human T cell populations and functions.
  • Ability to independently design and execute research plans for one or more programs, and to review, analyze, and interpret experimental results.
  • Ability to draft, execute and record protocols and experiments in a timely manner and maintain an excellent laboratory notebook.
  • Job complexity is high and requires ability to work with high degree of independence.
  • Strong interpersonal, influencing, negotiating and collaboration skills together with evidence of having used these to support problem solving and delivery in a team-oriented, collaborative environment.
  • Proven track record of success in your research and experience preparing written scientific reports and oral presentations.

Desirable Requirements
  • Post-doctoral training is preferred.
  • Experience working with high-dimensional analyses (flow cytometric or genomic) is an advantage.

AstraZeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers.

So, what's next?

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!

If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: July 16, 2022

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

As part of the application process for some roles at AstraZeneca, candidates may be asked to complete a series of online games, created by pymetrics, to assess certain candidate qualities to help evaluate potential match for the position. If the pymetrics process applies to this role, you will receive an email invitation with additional information following application. Once completed AZ will automatically receive your results - pymetrics will not be used solely in our decision-making process but will help us gather additional insight.



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